For more detailed information on vaccinations, please see the CANIBD Vaccination Guide
Chest X-ray TB skin test Blood work (baseline CBC, renal and liver function, HBV)
Ensure all immunizations are current. Wait at least four weeks to start following administration of live vaccination. Pneumococcal vaccination recommended for adult patients. Recommend vaccinations: HAV, HBV, HPV, and Tdap Refer to CANIBD Vaccination Guidelines for further information.9
Use with caution in patients with chronic or recurrent infection.
METHOD OF ADMINISTRATION
IV Infusion
LOCATION
Infusion centre
DOSING
Weight-based dosing. Standard dose is 5 mg/kg.
Induction: wk 0, wk 2, wk 6,
then maintenance every 8 wks*
Pediatric Dosing:
(≥ 9 years of age) with moderately to severely active Crohn’s disease:
5 mg/kg given as an induction regimen at 0, 2 and 6 weeks
followed by a maintenance regimen of 5 mg/kg every 8 weeks.
The safety and efficacy of Remicade® has not been established in pediatric patients with Crohn’s disease <9 years of age.
TIME REQUIRED
3-4 hrs
Those who do not experience a reaction can be infused <2 hrs
ROUTINE
MONITORING
Annual cervical cancer screening – pap test
Annual skin exam – skin malignancies
Influenza vaccine recommended
May consider therapeutic drug monitoring (TDM) if available
Screening for osteoporosis with bone mineral density testing periodically after diagnosis