PRE-TESTING AND VACCINATION

For more detailed information on vaccinations, please see the CANIBD Vaccination Guide

Chest X-ray
TB skin test
Blood work (baseline CBC, renal and liver function, HBV)

Ensure all immunizations are current.
Wait at least four weeks to start following administration of live vaccination.
Pneumococcal vaccination recommended for adult patients.
Recommend vaccinations: HAV, HBV, HPV, and Tdap
Refer to CANIBD Vaccination Guidelines for further information.9

Use with caution in patients with chronic or recurrent infection.

METHOD OF ADMINISTRATION

IV Infusion

LOCATION

Infusion centre

DOSING

Weight-based dosing. Standard dose is 5 mg/kg.

Induction:  wk 0, wk 2, wk 6,

then maintenance every 8 wks*

 

Pediatric Dosing:

(≥ 9 years of age) with moderately to severely active Crohn’s disease:

5 mg/kg given as an induction regimen at 0, 2 and 6 weeks

followed by a maintenance regimen of 5 mg/kg every 8 weeks.

The safety and efficacy of Remicade® has not been established in pediatric patients with Crohn’s disease <9 years of age.

TIME REQUIRED

3-4 hrs

Those who do not experience a reaction can be infused <2 hrs

ROUTINE MONITORING

Annual cervical cancer screening – pap test

Annual skin exam – skin malignancies

Influenza vaccine recommended

May consider therapeutic drug monitoring (TDM) if available

Screening for osteoporosis with bone mineral density testing periodically after diagnosis