PRE-TESTING AND VACCINATION

For more detailed information on vaccinations, please see the CANIBD Vaccination Guide12

TB skin test, blood work (baseline CBC, liver enzymes, lipids, CK, renal function, Hepatitis B serology)

Ensure all immunizations are current. Refer to CANIBD Vaccination Guidelines for further information.12

METHOD OF ADMINISTRATION

IV Infusion X3
Then SC injection

LOCATION

Infusion centre
Home

DOSING

Induction:
900 mg IV mg wk 0, wk 4, wk 8

Then maintenance 300 mg SC every 4 weeks.

TIME REQUIRED

Minimum 30-min infusion

Self-injection 5 min

ROUTINE MONITORING

Evaluate liver enzymes and bilirubin at baseline and every 1–4 months during induction (including induction period, if applicable) and thereafter according to standard practice.

Cervical cancer screening – pap test as per provincial guidelines

Annual skin exam – skin malignancies

Influenza vaccine recommended

Screening for osteoporosis with bone mineral density testing periodically after diagnosis