TB skin test, blood work (baseline CBC, liver enzymes, lipids, CK, renal function, Hepatitis B serology)
Ensure all immunizations are current. Refer to CANIBD Vaccination Guidelines for further information.12
METHOD OF ADMINISTRATION
IV Infusion X3 Then SC injection
LOCATION
Infusion centre Home
DOSING
Induction: 900 mg IV mg wk 0, wk 4, wk 8
Then maintenance 300 mg SC every 4 weeks.
TIME REQUIRED
Minimum 30-min infusion
Self-injection 5 min
ROUTINE
MONITORING
Evaluate liver enzymes and bilirubin at baseline and every 1–4 months during induction (including induction period, if applicable) and thereafter according to standard practice.
Cervical cancer screening – pap test as per provincial guidelines
Annual skin exam – skin malignancies
Influenza vaccine recommended
Screening for osteoporosis with bone mineral density testing periodically after diagnosis