Advanced Therapies in Crohn's Disease

PAEDIATRICS

Not currently approved for paediatric use.

ELDERLY

Clinical trials of vedolizumab did not include sufficient numbers of subjects aged 65+ to determine whether they respond differently from younger subjects.

PREGNANCY

In women with inflammatory bowel disease who are pregnant or attempting conception, we suggest continuing maintenance vedolizumab therapy throughout pregnancy.13

BREASTFEEDING

Mothers with IBD currently on anti-integrins may breastfeed.13