Advanced Therapies in Crohn's Disease

PAEDIATRICS

Not currently approved for paediatric use.

ELDERLY

Limited data. Population pharmacokinetic analysis showed no overall differences in mirikizumab exposure between older and younger subjects.

PREGNANCY
NEW GLOBAL
GUIDELINES

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Women with IBD who are pregnant or attempting conception should continue anti-IL23 therapy throughout pregnancy.13

BREASTFEEDING

Mothers with IBD currently on anti-IL 12/23 and anti-IL23 agents may breastfeed.13