Advanced Therapies in Crohn's Disease

PAEDIATRICS

Not currently approved for paediatric use.

ELDERLY

For patients older than 65 years of age, the recommended maintenance dose is 15mg once daily.

PREGNANCY
NEW GLOBAL
GUIDELINES

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Women with IBD should discontinue upadacitinib at least 4 weeks prior to conception unless there is no effective alternative therapy to maintain maternal health.13

BREASTFEEDING

Mothers with IBD currently on JAKi should not breastfeed.13