Advanced Therapies in Crohn's Disease

PAEDIATRICS

Not currently approved for paediatric use.

ELDERLY

Clinical trials of vedolizumab did not include sufficient numbers of subjects aged 65+ to determine whether they respond differently from younger subjects.

PREGNANCY
NEW GLOBAL
GUIDELINES

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In women with inflammatory bowel disease who are pregnant or attempting conception, we suggest continuing maintenance vedolizumab therapy throughout pregnancy.13

BREASTFEEDING

Mothers with IBD currently on anti-integrins may breastfeed.13